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Murexide ( CAS: 3051-09-0 ) is a historically critical analytical reagent, widely used as a complexometric indicator for calcium, rare earth elements, and specific metal ions in high-precision titrations. With evolving quality requirements and environmental standards, the demand for highly pure, consistent murexide continues to trend upwards, especially for laboratories, metallurgy, petrochemicals, and water treatment sectors. This page offers an in-depth industry-level review of murexide —from manufacturing processes, technical data, and competitive positioning, to customization solutions and application cases. For detailed product info, visit the Murexide Product Page . Market Trends (2023-2024): Murexide global sales volume increased by 11.8% year-over-year, driven by analytical chemistry labs and advanced metallurgy. Quality demand for CAS 3051-09-0 variants ≥99% purity is rising, especially in European and East Asian markets. Source: ChemGlobal Insights, 2024. Technical Data Overview: Murexide (CAS 3051-09-0) Core Specifications Parameter Typical Value Industry Standard Test Method Notes Molecular Formula C8H8N6O6 — — Empirical formula Molecular Weight 284.19 g/mol — — — Appearance Purple powder ISO 8130-1 Visual Should be clean, uniform color Purity ≥ 99% ISO/IEC 17025 HPLC Lab/Analytical grade Solubility (Water) Moderate — 20°C, 1g/50ml — pH (1% solution) 5.5~6.8 ISO 10523 pH Meter Neutral range Shelf Life ≥ 3 years — Stability Test Sealed, dark, dry storage Origin China, India, Germany — — Major supply markets CAS Number 3051-09-0 Cas.org CAS Registry Check Universal registry Image: Murexide (3051-09-0) high-purity powder. Manufacturing Process Flow: Murexide Production Demystified Purine Base Separation Extraction of uric acid from natural sources ➤ Oxidative Synthesis Nitric acid oxidation of uric acid to Alloxan & Alloxantin ➤ Fusion & Condensation Ammonia+Alloxantin condensed to Murexide ➤ Purification Crystallization & ISO-based Fine Filtration ➤ Quality Inspection HPLC analysis, visual/colorimetric check Note: Key equipment includes high-purity reactors (316L SS), automated filtration units, and precision drying chambers. All plants must meet ISO 9001 and/or ISO/IEC 17025 laboratory analysis grade specifications. Key Technology Advantages and Performance Metrics Ultra-high Purity : Proprietary process achieves ≥99% purity ( ISO/IEC 17025 verified), ensuring exceptional endpoint sensitivity. Batch Consistency : Statistical QC ensures <0.8% batch-to-batch deviation, up to 15% higher than global niche competitors. Corrosion Resistance : Manufacturing plant uses acid-resistant lined reactors extending major equipment lifetime by 40% ( ASTM D1384 tested). Custom Particle Control : CNC sieving and cryogenic grinding for adjustable particle size from 20 μm (fine) to 80 μm (standard)—improves solubility and titration flow. Stability : 3-year shelf life guarantee in ISO-packaging. Eco-compliance : Effluent treatment per REACH and RoHS requirements. Certified Quality : Conforms to ISO 9001 , FDA (analytical), and China GB/T 19001 standards. Product Comparison: Murexide vs. Competing Complexometric Indicators Parameter Murexide (CAS 3051-09-0) Eriochrome Black T Calmagite Xylenol Orange Chemical Group Purine derivative Azodye Naphtholsulfonic acid Triphenylmethane Color Change (EDTA Ca 2+ titration) Purple → Pink Blue → Red Wine Red → Blue Red → Yellow Sensitivity (μmol/L) ~1 ~4 ~3 ~3-4 Solubility in Water Moderate Low Good Good Typical Application Calcium/Rare earths Mg, Ca (hardness) Mg, Ca Fe, Zn Environmental Profile Eco safer (ISO) Moderate Moderate Classic (RoHS) Main Application Scenarios & Competitive Advantages Analytical Laboratories (39%) : Murexide remains the indicator of choice for high-precision EDTA titrations to quantify Ca 2+ , rare earths (Yttrium, Thorium), and some transition metals due to its pronounced color endpoint and high sensitivity. Metallurgy (24%) : Used for purity control of rare earth oxides and process titrations in aluminum, magnesium, and rare metal refining, withstand aggressive media thanks to advanced corrosion resistance. Petrochemicals (18%) : Cation balance analysis, catalyst quality assurance—excellent stability even in high-salt process streams. Water Treatment (12%) : For quick, accurate hardness determination and monitoring of Ca/Mg/Cu in municipal/industrial water; compatible with automated water analysis stations. Advantages: Fast response, reduced reagent consumption, and minimal toxicity ( ISO 17034 verified). Research/Other (7%) : Used for academic chemical studies, educational demonstration, and novel chelating agent development. Case: CAS 3051-09-0 high-purity powder in industry titration setup. Leading Manufacturers / Vendors: Murexide Global Comparison Vendor Origin Purity Spec (%) Main Certifications MOQ (g) Response Time Website MoneideChem China 99.3 ISO 9001, ISO/IEC 17025 25 <12h Product Link Alfa Aesar UK/US 99.0 REACH, ISO 10 24h Alfa Aesar TCI Chemicals Japan 98.5 ISO, FDA 5 24-48h TCI Japan Merck/Sigma Germany/US 98.0 ISO 17025 10 24h Merck/Sigma Customization & Integration Solutions Particle Size Customization : CNC-milled or micronized per user process (20–80 μm range), with optional lot traceability coding. Private Label Services : Custom labeling, certificate of analysis embedding, and %purity imprint for major clients (meets ISO 17034 ). Formulation Control : Ability to pre-mix murexide with auxiliary buffer solutions in client-designated ratios, ready for direct use. Compliance Documentation : Full supply of analytical grade data sheets, MSDS/SDS, and import/export compliance for CAS 3051 09 0 . Technical Support : Fast-response analytical chemist (minimum 15 years field experience) consults, ISO/FDA compliant batch reports, annual stability tests. Industry Partnerships : OEM solutions for reagent kit brands (Europe/Asia), integration with automated titration platforms. Looking for a tailored murexide solution? Contact us for a free sample testing or custom specification quote. Application Case Studies & Client References Case 1: National Laboratory Chain (Europe, 2022) Switched to murexide from MoneideChem for calcium titration kits. Achieved 17% faster endpoint recognition vs. Eriochrome Black T in hard water samples. Lab director praised batch consistency for ISO 17025 audits. Case 2: Petrochemical Major (Asia, 2023) Integrated CAS 3051 09 0 lot with automated robotic titration unit. Demonstrated No.1 endpoint discrimination with 0.6% repeatability variance . Cost savings on reagent volume by 9% year-over-year. Case 3: College Teaching Labs Adopted colored, milligram-dosed murexide mini-packs for undergraduate analytical courses. Feedback: vivid endpoint, safer handling, zero allergic complaints, and excellent shelf stability. Quality, Warranty, Support & Compliance Commitments Certification : All murexide supplied meets ISO 9001 , ISO/IEC 17025 , and (for food/lab use) FDA requirements. Batch Testing : Each lot accompanied by independent HPLC, purity assay, and heavy metals screening report; accessible via QR code. Warranty : Minimum 3-year shelf-life in sealed, original ISO packaging; replacement or refund if test data deviate from specs. Delivery : 0–1 business day production cycle, standard air express, DAP/FCA/FOB. Customer Support : 1:1 chemist hotline, consultative technical troubleshooting within 8h; full MSDS in English/Chinese. FAQ: Murexide (3051-09-0) Technical FAQ Q1: What is the chemical nature and CAS reference for murexide ? Murexide is chemically a purpuric acid ammonium salt (C8H8N6O6), with a CAS number 3051-09-0 , renowned for its chromatic endpoint and high metal selectivity in complexometric analysis. Q2: What are the standard specifications and quality benchmarks? Standard quality benchmarks for murexide include purity ≥99% (ISO/IEC 17025 validated), minimal heavy metals, moisture ≤0.2%, and smooth, homogenous free-flowing purple powder. Each batch is issued with a certificate of analysis. Q3: How to store murexide for the best shelf life? Store murexide in a tightly sealed, light-proof container111, at room temperature (<25°C), in a dry, ventilated place. Recommended shelf life is 3 years when unopened; ISO storage conditions advised. Q4: Is murexide compatible with automated titration systems? Yes. Thanks to precise micronization and formulation consistency, murexide formats are fully compatible with robotic titrators, auto-dispensers, and most automated EDTA titration platforms, both for water and non-aqueous matrices. Q5: What certifications are offered? Depending on intended use (analytical, teaching, or R&D), murexide can be supplied with ISO 9001, ISO/IEC 17025, FDA (lab grade), and/or REACH/RoHS certification. Q6: What is the lead time and minimum order? For regular grades, MOQ is as low as 5~25g for R&D shipment, with production within 0–1 business day, and standard international delivery (FedEx/UPS/DHL) between 3–6 days. Q7: What are the safety and environmental standards followed? Murexide is produced under ISO 14001-compliant processes, with in-plant effluent management and RoHS-compliant residues. Main product and secondary packaging carry hazard and disposal guidance per local GHS standards. References & Further Reading Rare-earth complexometry review: Analytical Chemistry, ACS Publications Murexide market data: ChemNet: Global Chemical Index Indicator technique standards: ISO 8130-1:2017 Industry forum live QA: ResearchGate Chemistry Forum - EDTA Indicators